17-PA
17-PA is a selective antagonist of neurosteroid potentiation and direct gating of GABAA receptors[1].
Product Specifications
CAS Number
[694438-95-4]
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/17-pa.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12C(C3=CC=CC=C3)=CC[C@@]1([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)CC[C@]5(C)[C@@]4([H])CC2
Molecular Formula
C25H34O
Molecular Weight
350.54
References & Citations
[1]Mennerick S, et al. Selective antagonism of 5alpha-reduced neurosteroid effects at GABA (A) receptors. Mol Pharmacol. 2004 May;65 (5) :1191-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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