RU58668

RU58668 is a steroidal antiestrogen that can be used as a potent antiproliferative agent on MCF-7 cells. RU58668 has the potential for the breast cancer research[1].

Product Specifications

CAS Number

[151555-47-4]

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/ru58668.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])[C@@H](C5=CC=C(OCCCCCS(=O)(CCCC(F)(F)C(F)(F)F)=O)C=C5)C2

Molecular Formula

C34H43F5O5S

Molecular Weight

658.76

References & Citations

[1]P Van de Velde, et al. RU 58,668, a new pure antiestrogen inducing a regression of human mammary carcinoma implanted in nude mice. J Steroid Biochem Mol Biol. 1994 Feb;48 (2-3) :187-96.