EGFR-IN-80
EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1].
Product Specifications
CAS Number
[171745-13-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-80.html
Solubility
10 mM in DMSO
Smiles
CCOC1=CC2=NC=NC(NC3=CC=CC(Br)=C3)=C2C=C1OCC
Molecular Formula
C18H18BrN3O2
Molecular Weight
388.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Farhan Ahmad Pasha, et al. In silico QSAR studies of anilinoquinolines as EGFR inhibitors. J Mol Model. 2010 Feb;16 (2) :263-77.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
Curated Selection
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