Quinelorane (dihydrochloride)

Quinelorane dihydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research[1][2].

Product Specifications

CAS Number

[97548-97-5]

Product Name Alternative

LY163502

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/quinelorane-dihydrochloride.html

Purity

99.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=NC=C2C[C@]3([H])[C@@](CCCN3CCC)([H])CC2=N1.[H]Cl.[H]Cl

Molecular Formula

C14H24Cl2N4

Molecular Weight

319.27

References & Citations

[1]Ying Qu, et al. Quinelorane, a dopamine D3/D2 receptor agonist, reduces prepulse inhibition of startle and ventral pallidal GABA efflux: time course studies. Pharmacol Biochem Behav. 2008 Oct;90 (4) :686-90.|[2]Morgane Thomsen, et al. Psychomotor stimulation by dopamine D₁-like but not D₂-like agonists in most mouse strains. Exp Clin Psychopharmacol. 2011 Oct;19 (5) :342-60.