Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SKF83822 (hydrobromide)

SKF83822 hydrobromide is a potent dopamine D1 receptor agonist. SKF83822 hydrobromide activates Gs/olf/adenylyl cyclase (AC) -coupled D1 receptors, but not phospholipase C (PLC) -coupled D1-like receptors[1].

Product Specifications

CAS Number

[74115-10-9]

UNSPSC

12352005

Hazard Statement

H301-H400

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/skf83822-hydrobromide.html

Solubility

10 mM in DMSO

Smiles

OC1=C(O)C=C2C(C3=CC=CC(C)=C3)CN(CC=C)CCC2=C1Cl.[H]Br

Molecular Formula

C20H23BrClNO2

Molecular Weight

424.76

Precautions

P264-P270-P273-P330-P391-P405-P501

References & Citations

[1]Mahomi Kuroiwa, et al. Regulation of DARPP-32 phosphorylation by three distinct dopamine D1-like receptor signaling pathways in the neostriatum. J Neurochem. 2008 Nov;107 (4) :1014-26.|[2]Aliya L Frederick, et al. Neurobehavioral phenotyping of G (αq) knockout mice reveals impairments in motor functions and spatial working memory without changes in anxiety or behavioral despair. Front Behav Neurosci. 2012 Jun 19;6:29.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-103411/SKF83822-hydrobromide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-103411/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

D1 Receptor

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Rint1 Pre-designed siRNA Set B
SI112009B 1 Each

Mouse Rint1 Pre-designed siRNA Set B

Ask
View Details
Casein kinase Iα shRNA Plasmid (m)
sc-29913-SH 20 µg

Casein kinase Iα shRNA Plasmid (m)

Ask
View Details
AOX1 shRNA Plasmid (r)
sc-270303-SH 20 µg

AOX1 shRNA Plasmid (r)

Ask
View Details
BHMT2 CRISPRa sgRNA lentivector (set of three targets)(Human)
13317121 3 x 1.0μg DNA

BHMT2 CRISPRa sgRNA lentivector (set of three targets)(Human)

Ask
View Details
Mouse CPNE7 ELISA Kit
E079952 1 Each

Mouse CPNE7 ELISA Kit

Ask
View Details