(-) -OSU6162 (hydrochloride)

(-) -OSU6162 (PNU96391) hydrochloride is a dopamine stabilizer. (-) -OSU6162 hydrochloride acts as partial agonist at 5-HT2A and is a dopamine D2 antagonist. (-) -OSU6162 hydrochloride can be used for the research of aggression and irritability[1][2].

Product Specifications

CAS Number

[156907-84-5]

Product Name Alternative

PNU96391 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H319

Target

5-HT Receptor; Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/minus-osu6162-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CCCN1C[C@H](C2=CC=CC(S(=O)(C)=O)=C2)CCC1.[H]Cl

Molecular Formula

C15H24ClNO2S

Molecular Weight

317.87

Precautions

H302, H319

References & Citations

[1]Carlsson ML, et al. I. In vivo evidence for partial agonist effects of (-) -OSU6162 and (+) -OSU6162 on 5-HT2A serotonin receptors. J Neural Transm (Vienna) . 2011 Nov;118 (11) :1511-22.|[2]Studer E, et al. The effects of the dopamine stabilizer (-) -OSU6162 on aggressive and sexual behavior in rodents. Transl Psychiatry. 2016 Mar 22;6 (3) :e762.