NIDA-41020
NIDA-41020 is a potent and selective cannabinoid receptor 1 (CB1) antagonist with a Ki of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET) [1].
Product Specifications
CAS Number
502486-89-7
UNSPSC
12352005
Hazard Statement
H300-H315-H319-H335
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nida-41020.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C(C2=CC=C(OC)C=C2)=C1C)C3=CC=C(C=C3Cl)Cl)NN4CCCCC4
Molecular Formula
C23H24Cl2N4O2
Molecular Weight
459.37
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Katoch-Rouse R, et al. Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity. J Med Chem. 2003 Feb 13;46 (4) :642-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1
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