[Phe8Ψ (CH-NH) Arg9]-Bradykinin

[Phe8Ψ (CH-NH) Arg9]-Bradykinin is a selective Bradykinin receptor B2 agonist (not cleaved by protein kinase I/II) . [Phe8Ψ (CH-NH) Arg9]-Bradykinin has potential for the research of hypertension[1].

Product Specifications

CAS Number

[118122-39-7]

UNSPSC

12352209

Target

Bradykinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/phe8-ch-nh-arg9-bradykinin.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CCC1)C(NCC(N[C@H](C(N[C@@H](CO)C(N2[C@@H](CCC2)C(N[C@H](CN[C@H](C(O)=O)CCCNC(N)=N)CC3=CC=CC=C3)=O)=O)=O)CC4=CC=CC=C4)=O)=O)[C@H]5N(CCC5)C([C@@H](N)CCCNC(N)=N)=O

Molecular Formula

C50H75N15O10

Molecular Weight

1046.23

References & Citations

[1]Drapeau G, et al. [Phe8 psi (CH2-NH) Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Eur J Pharmacol. 1988 Oct 11;155 (1-2) :193-5.