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GRP (porcine)

GRP (porcine) (Porcine gastrin-releasing peptide 27) is the putative mammalian analog of Bombesin. GRP (porcine) activates the release of a number of gastroenteropancreatic (GEP) peptides into the peripheral circulation. GRP (porcine) stimulates gastrin release and exocrine pancreatic secretion. GRP (porcine) is a useful marker of neuroendocrine differentiation in many tumors[1][2].

Product Specifications

CAS Number

74815-57-9

Product Name Alternative

Porcine gastrin-releasing peptide 27

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/grp-porcine.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(CCC1)C([C@@H](NC([C@H](CCSC)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@@]([C@H](O)C)([H])NC(CNC(CNC(CNC([C@H](C(C)C)NC([C@H](CO)NC([C@H](C(C)C)NC([C@H]2N(CCC2)C([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CNC=N4)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)CC5=CNC=N5)=O)=O)=O)=O)CC6=CNC7=C6C=CC=C7)=O)=O)=O)=O

Molecular Formula

C126H198N38O31S2

Molecular Weight

2805.29

References & Citations

[1]McDonald TJ, et al. The effect of gastrin-releasing peptide on the endocrine pancreas. Ann N Y Acad Sci. 1988;547:242-54.|[2]Bostwick DG, Bensch KG. Gastrin releasing peptide in human neuroendocrine tumours. J Pathol. 1985 Dec;147 (4) :237-44.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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