NPEC-caged- (S) -AMPA

NPEC- caged- (S) -AMPA, a caged neurotransmitter analog, is a NPEC photoprotecting group caged the (S) -AMPA (HY-100815A) to make caged ligands specific for glutamate receptor sub-types. NPEC- caged- (S) -AMPA selectively activates AMPA receptor[1].

Product Specifications

CAS Number

[1257323-84-4]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/npec-caged-s-ampa.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C[C@@H](C(O)=O)NC(OC(C2=C(C=CC=C2)[N+]([O-])=O)C)=O)=C(C)ON1

Molecular Formula

C16H17N3O8

Molecular Weight

379.32

References & Citations

[1]Francisco Palma-Cerda, et al. New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 2012 Sep;63 (4) :624-34.