GYKI 52466
GYKI 52466 is an orally active, highly selective and noncompetitive AMPA/kainate receptor antagonist with the IC50 values of 7.5 and 11μM, respectively. GYKI 52466 has good blood brain barrier permeability and anticonvulsant effect. GYKI 52466 can be used in Parkinson's disease research[1][2].
Product Specifications
CAS Number
102771-26-6
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gyki-52466.html
Solubility
10 mM in DMSO
Smiles
NC1=CC=C(C2=NN=C(C)CC3=CC4=C(OCO4)C=C32)C=C1
Molecular Formula
C17H15N3O2
Molecular Weight
293.32
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor; Kainate Receptor
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
LIVEO Pharma-50 platinum cured silicone tubing
TMEM151A CRISPR All-in-one AAV vector set (with saCas9)(Rat)
