SDZ-WAG994

SDZ-WAG994 (WAG-994) is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation[1].

Product Specifications

CAS Number

[130714-47-5]

Product Name Alternative

WAG-994; N6-Cyclohexy-2'-0-methyladenosine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sdz-wag994.html

Solubility

10 mM in DMSO

Smiles

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC4CCCCC4

Molecular Formula

C17H25N5O4

Molecular Weight

363.41

Precautions

H302, H315, H319, H335

References & Citations

[1]O Piot, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21 (11 Pt 2) :2459-64.|[2]Wagner H, et al. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist. Drug development research, 1995, 34 (3) : 276-288.|[3]Piot O, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21 (11 Pt 2) :2459-64.