PSB11 (hydrochloride)
PSB11 hydrochloride is an antagonist with reverse excitatory activity for human A3 Adenosine Receptor with high affinity (Ki=2.3 nM) [1].
Product Specifications
CAS Number
453591-58-7
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/psb11-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)C2=C(N=C(C3=CC=CC=C3)N2)C4=N[C@H](CC)CN14.[H]Cl
Molecular Formula
C16H18ClN5O
Molecular Weight
331.80
References & Citations
[1]Müller C E, et al. [3H] 8-Ethyl-4-methyl-2-phenyl- (8R) -4, 5, 7, 8-tetrahydro-1H-imidazo [2, 1-i]-purin-5-one ([3H] PSB-11), a novel high-affinity antagonist radioligand for human A3 adenosine receptors[J]. Bioorganic & medicinal chemistry letters, 2002, 12 (3) : 501-503.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A3 receptor (A3R)
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