SB-216641A
SB-216641A (SB-216641 hydrochloride) is a selective antagonist of 5-HT1B/D receptor. SB-216641A shows high affinity and selectivity for h5-HT1B receptors over h5-HT1D receptors. SB-216641A inhibits the function of SKF-99101H[1][2].
Product Specifications
CAS Number
193611-67-5
Product Name Alternative
SB-216641 (hydrochloride)
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-216641a.html
Purity
98.0
Solubility
H2O : 26.15 mg/mL (ultrasonic; warming) |DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C2=C(C)C=C(C3=NOC(C)=N3)C=C2)C=C1)NC4=CC=C(C(OCCN(C)C)=C4)OC.Cl
Molecular Formula
C28H31ClN4O4
Molecular Weight
523.02
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3
Available Sizes
Frequently Asked Questions
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