Lotrafiban

Lotrafiban is an orally-active platelet GPIIb/IIIa blocker for research of coronary and cerebrovascular disease.

Product Specifications

CAS Number

[171049-14-2]

Product Name Alternative

SB-214857

UNSPSC

12352005

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/lotrafiban.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C)CC2=CC(C(N3CCC(C4CCNCC4)CC3)=O)=CC=C2N[C@H]1CC(O)=O

Molecular Formula

C23H32N4O4

Molecular Weight

428.52

References & Citations

[1]Topol EJ, Easton D, Harrington RA, et al. Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease. Circulation. 2003;108 (4) :399-406.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

Curated Selection

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