Lotrafiban
Lotrafiban is an orally-active platelet GPIIb/IIIa blocker for research of coronary and cerebrovascular disease.
Product Specifications
CAS Number
[171049-14-2]
Product Name Alternative
SB-214857
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lotrafiban.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)CC2=CC(C(N3CCC(C4CCNCC4)CC3)=O)=CC=C2N[C@H]1CC(O)=O
Molecular Formula
C23H32N4O4
Molecular Weight
428.52
References & Citations
[1]Topol EJ, Easton D, Harrington RA, et al. Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease. Circulation. 2003;108 (4) :399-406.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Curated Selection
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