Altanserin (hydrochloride)
Altanserin is a 5-hydroxytryptamine (5-HT2A) selective radioligand. Altanserin delivers human serotonin. Altanserin can be used to study the biochemical and cellular mechanisms of vulnerability to extracellular 5-HT increase [1].
Product Specifications
CAS Number
1135280-78-2
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/altanserin-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)C(NC4=C1C=CC=C4)=S.Cl
Molecular Formula
C22H23ClFN3O2S
Molecular Weight
447.95
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Pinborg LH, et al. [18F]altanserin binding to human 5HT2A receptors is unaltered after citalopram and pindolol challenge. J Cereb Blood Flow Metab. 2004 Sep;24 (9) :1037-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
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