Altanserin (hydrochloride)

Altanserin is a 5-hydroxytryptamine (5-HT2A) selective radioligand. Altanserin delivers human serotonin. Altanserin can be used to study the biochemical and cellular mechanisms of vulnerability to extracellular 5-HT increase [1].

Product Specifications

CAS Number

[1135280-78-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/altanserin-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C1N(CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)C(NC4=C1C=CC=C4)=S.Cl

Molecular Formula

C22H23ClFN3O2S

Molecular Weight

447.95

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Pinborg LH, et al. [18F]altanserin binding to human 5HT2A receptors is unaltered after citalopram and pindolol challenge. J Cereb Blood Flow Metab. 2004 Sep;24 (9) :1037-45.