SB 206553 (hydrochloride)
SB 206553 hydrochloride is a high affinity, selective and orally active 5-HT2B / 5-HT2C receptor antagonist (rat 5-HT2B pA2 = 8.89, human 5-HT2C pKi = 7.92) [1]. SB 206553 possesses anxiolytic-like properties[2].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-206553-hydrochloride.html
Purity
99.36
Solubility
DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1C(C(CC1)=C2)=CC3=C2N(C)C=C3)NC4=CC=CN=C4.[H]Cl
Molecular Formula
C17H17ClN4O
Molecular Weight
328.80
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103135/SB-206553-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103135/SB-206553-hydrochloride-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
CAS Number
[1197334-04-5]
Available Sizes
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