MS 245 (oxalate)
MS 245 oxalate is a potent antagonist of 5-HT6 receptor with a Ki of 2 nM[1].
Product Specifications
CAS Number
275363-58-1
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ms-245-oxalate.html
Solubility
10 mM in DMSO
Smiles
O=S(N1C=C(CCN(C)C)C2=C1C=CC(OC)=C2)(C3=CC=CC=C3)=O.O=C(O)C(O)=O
Molecular Formula
C21H24N2O7S
Molecular Weight
448.49
References & Citations
[1]Abate C, et al. Interaction of chiral MS-245 analogs at h5-HT6 receptors. Bioorg Med Chem Lett. 2005;15 (15) :3510-3513.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor
Frequently Asked Questions
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