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PI3K-IN-32

PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC50 of 6.85[1].

Product Specifications

CAS Number

[371934-59-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3k-in-32.html

Purity

99.7

Solubility

DMSO : 3.5 mg/mL (ultrasonic; warming)

Smiles

NC1=CC=CC(C2=NC(N3CCOCC3)=C(OC4=NC=CC=C45)C5=N2)=C1

Molecular Formula

C19H17N5O2

Molecular Weight

347.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Li Y, et al. Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110alpha inhibitors. J Mol Model. 2010 Sep;16 (9) :1449-60.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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