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Flovagatran

Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM) . Flovagatran can be used in the research of arterial and venous thrombosis[1].

Product Specifications

CAS Number

871576-03-3

Product Name Alternative

TGN 255

UNSPSC

12352005

Target

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/flovagatran.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC1=CC=CC=C1)N[C@H](CC2=CC=CC=C2)C(N3CCC[C@H]3C(N[C@@H](CCCOC)B(O)O)=O)=O

Molecular Formula

C27H36BN3O7

Molecular Weight

525.40

References & Citations

[1]Nelson DA, et al. Pharmacodynamic and efficacy profile of TGN 255, a novel direct thrombin inhibitor, in canine cardiopulmonary bypass and simulated mitral valve repair. J Extra Corpor Technol. 2008 Jun;40 (2) :116-22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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