Flovagatran
Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM) . Flovagatran can be used in the research of arterial and venous thrombosis[1].
Product Specifications
CAS Number
871576-03-3
Product Name Alternative
TGN 255
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/flovagatran.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=CC=C1)N[C@H](CC2=CC=CC=C2)C(N3CCC[C@H]3C(N[C@@H](CCCOC)B(O)O)=O)=O
Molecular Formula
C27H36BN3O7
Molecular Weight
525.40
References & Citations
[1]Nelson DA, et al. Pharmacodynamic and efficacy profile of TGN 255, a novel direct thrombin inhibitor, in canine cardiopulmonary bypass and simulated mitral valve repair. J Extra Corpor Technol. 2008 Jun;40 (2) :116-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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