LY-517717
LY-517717 is a potent and orally active FXa inhibitor. LY-517717 shows antithrombotic and anticoagulant activity. LY-517717 has the potential for the research of venous thromboembolism after hip or knee replacement[1].
Product Specifications
CAS Number
313489-71-3
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ly-517717.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(C2CCN(C)CC2)CC1)[C@@H](C3=CC=CC=C3)NC(C(C=C4)=CC5=C4C=CN5)=O
Molecular Formula
C27H33N5O2
Molecular Weight
459.58
References & Citations
[1]Agnelli G, et al. A phase II study of the oral factor Xa inhibitor LY517717 for the prevention of venous thromboembolism after hip or knee replacement. J Thromb Haemost. 2007 Apr;5 (4) :746-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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