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LY-517717

LY-517717 is a potent and orally active FXa inhibitor. LY-517717 shows antithrombotic and anticoagulant activity. LY-517717 has the potential for the research of venous thromboembolism after hip or knee replacement[1].

Product Specifications

CAS Number

313489-71-3

UNSPSC

12352005

Target

Factor Xa

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ly-517717.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN(C2CCN(C)CC2)CC1)[C@@H](C3=CC=CC=C3)NC(C(C=C4)=CC5=C4C=CN5)=O

Molecular Formula

C27H33N5O2

Molecular Weight

459.58

References & Citations

[1]Agnelli G, et al. A phase II study of the oral factor Xa inhibitor LY517717 for the prevention of venous thromboembolism after hip or knee replacement. J Thromb Haemost. 2007 Apr;5 (4) :746-53.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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