Betrixaban-d6

Betrixaban-d6 is a deuterium labeled Betrixaban. Betrixaban is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor[1].

Product Specifications

CAS Number

[2098655-51-5]

Product Name Alternative

PRT054021-d6

UNSPSC

12352005

Hazard Statement

H302, H373

Target

Factor Xa

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Purity

99.02

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)NC2=C(C=C(C=C2)OC)C(NC3=CC=C(C=N3)Cl)=O

Molecular Formula

C23H16D6ClN5O3

Molecular Weight

457.94

Precautions

H302, H373

References & Citations

[1]Zhang P, et al. Discovery of Betrixaban (PRT054021), N- (5-chloropyridin-2-yl) -2- (4- (N, N-dimethylcarbamimidoyl) benzamido) -5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor. Bioorg Med Chem Lett. 2009 Apr 15;19 (8) :21.