Rapamycin-13C, d3
Rapamycin-13C, d3 (Sirolimus-13C, d3) is the 13C and deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant[1][2].
Product Specifications
Product Name Alternative
Sirolimus-13C, d3; AY-22989-13C, d3; NSC 226080-13C, d3
UNSPSC
12352005
Target
Antibiotic; Autophagy; Bacterial; Endogenous Metabolite; FKBP; Fungal; Isotope-Labeled Compounds; mTOR
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Purity
97.05
Solubility
10 mM in DMSO
Smiles
Molecular Formula
C50 13CH76D3NO13
Molecular Weight
918.18
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
FKBP12
Available Sizes
Frequently Asked Questions
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