BET-IN-2
BET-IN-2 is a BET inhibitor with an IC50 of 52 nM for BRD4-BD1.
Product Specifications
CAS Number
2104688-91-5
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BET-IN-2.html
Solubility
10 mM in DMSO
Smiles
CC1=C([C@H](C)NC2=CC(N(C3CC3)[C@H](C)C(N4C)=O)=C4C=C2)C=CC(C)=C1
Molecular Formula
C23H29N3O
Molecular Weight
363.50
References & Citations
[1]Hu J, et al. Discovery of a series of dihydroquinoxalin-2 (1H) -ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor. Eur J Med Chem. 2017 Sep 8;137:176-195.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![8-Bromo-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
FDC56885-01 0.5 g
8-Bromo-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride
Sign In for Pricing
View Details FDC56885-02 5 g
8-Bromo-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride
Sign In for Pricing
View Details 
MBS745774-01 48 Well
Canine Basic fibroblast growth factor 9 ELISA Kit
Sign In for Pricing
View Details MBS745774-02 96 Well
Canine Basic fibroblast growth factor 9 ELISA Kit
Sign In for Pricing
View Details MBS745774-03 5x 96 Well
Canine Basic fibroblast growth factor 9 ELISA Kit
Sign In for Pricing
View Details