SMBA1
SMBA1 is a potent Bax agonist with a Ki value of 43.3 nM. SMBA1 enhances the Bax expression. SMBA1 shows anti-tumor activity. SMBA1 has the potential for the research of lung cancer[1].
Product Specifications
CAS Number
906440-37-7
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/smba1.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=CC=C1/C=C2C3=C(C4=C\2C=CC=C4)C=CC([N+]([O-])=O)=C3
Molecular Formula
C20H13NO3
Molecular Weight
315.32
References & Citations
[1]Xin M, et al. Small-molecule Bax agonists for cancer therapy. Nat Commun. 2014 Sep 17;5:4935.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax
Available Sizes
Frequently Asked Questions
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