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Uridine 5'-monophosphate-15N2

Uridine 5'-monophosphate-15N2 (5'-​Uridylic acid-15N2) is the 15N labeled Uridine 5'-monophosphate. Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea[1][2].

Product Specifications

Product Name Alternative

5'-​Uridylic acid-15N2

UNSPSC

12352005

Target

Apoptosis; Cholinesterase (ChE) ; Endogenous Metabolite; Isotope-Labeled Compounds; Potassium Channel

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/uridine-5-monophosphate-15n2.html

Purity

98.0

Solubility

DMSO : 150mg/mL (ultrasonic) |H2O : 150mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@]([H])(O[C@H](COP(O)(O)=O)[C@H]1O)[15N]2C([15NH]C(C=C2)=O)=O

Molecular Formula

C9H13 15N2O9P

Molecular Weight

326.17

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Li G, et al. Uridine/UMP metabolism and their function on the gut in segregated early weaned piglets. Food Funct. 2019 Jul 17;10 (7) :4081-4089.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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