CNS 5161
CNS-5161 is a novel NMDA ion-channel antagonist that interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.
Product Specifications
CAS Number
160754-76-7
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cns-5161.html
Solubility
10 mM in DMSO
Smiles
N=C(NC1=CC(SC)=CC=C1Cl)N(C)C2=CC=CC(SC)=C2
Molecular Formula
C16H18ClN3S2
Molecular Weight
351.92
References & Citations
[1]Walters MR, et al. Early clinical experience with the novel NMDA receptor antagonist CNS 5161. Br J Clin Pharmacol. 2002 Mar;53 (3) :305-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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