SCH 336
SCH 336 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice[1].
Product Specifications
CAS Number
[447459-51-0]
Product Name Alternative
SCH-225336
UNSPSC
12352005
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sch-336.html
Concentration
10mM
Purity
98.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CS(N[C@H](C1=CC=C(C=C1)S(C2=C(C=C(C=C2)OC)S(=O)(C3=CC=C(C=C3)OC)=O)(=O)=O)C)(=O)=O
Molecular Formula
C23H25NO8S3
Molecular Weight
539.64
References & Citations
[1]Lunn CA, et al. A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo. J Pharmacol Exp Ther. 2006 Feb;316 (2) :780-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB2
Available Sizes
Curated Selection
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