Cavidine
Cavidine ((+) -Cavidine) is a selective COX-2 inhibitor which possesses anti-inflammatory activity. Cavidine can be used for the research of skin injuries, hepatitis, cholecystitis, and scabies. Cavidine ameliorates LPS -induced acute lung injury via NF-κB signaling pathway[1][2][3].
Product Specifications
CAS Number
32728-75-9
Product Name Alternative
(+) -Cavidine
UNSPSC
12352005
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cavidine.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1C(C=C2)=C(C3=C2OCO3)CN4CCC5=CC(OC)=C(OC)C=C5[C@@]14[H]
Molecular Formula
C21H23NO4
Molecular Weight
353.41
References & Citations
[1]Niu X, et, al. Anti-inflammatory effects of cavidine in vitro and in vivo, a selective COX-2 inhibitor in LPS-induced peritoneal macrophages of mouse. Inflammation. 2015 Apr;38 (2) :923-33.|[2]Niu X, et, al. Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways. Chem Biol Interact. 2015 Sep 5:239:34-45.|[3]Niu X, et, al. Cavidine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via NF-κB Signaling Pathway in vivo and in vitro. Inflammation. 2017 Aug;40 (4) :1111-1122.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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