AUTEN-99 (hydrobromide)
AUTEN-99 (hydrobromide) is a novel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14) . AUTEN-99 (hydrobromide) crosses the blood-brain barrier and exerts potent neuroprotective effects[1].
Product Specifications
CAS Number
1049780-58-6
Product Name Alternative
Autophagy enhancer-99 (hydrobromide)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/auten-99-hydrobromide.html
Solubility
DMSO : ≥ 7.5 mg/mL
Smiles
[H]Br.C12=NCCN1C=C(C3=CC=C(C4=CC=CC=C4)C=C3)S2
Molecular Formula
C17H15BrN2S
Molecular Weight
359.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Kovács T, et al. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci Rep. 2017 Feb 16;7:42014.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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