AUTEN-99 (hydrobromide)

AUTEN-99 (hydrobromide) is a novel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14) . AUTEN-99 (hydrobromide) crosses the blood-brain barrier and exerts potent neuroprotective effects[1].

Product Specifications

CAS Number

[1049780-58-6]

Product Name Alternative

Autophagy enhancer-99 (hydrobromide)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/auten-99-hydrobromide.html

Solubility

DMSO : ≥ 7.5 mg/mL

Smiles

[H]Br.C12=NCCN1C=C(C3=CC=C(C4=CC=CC=C4)C=C3)S2

Molecular Formula

C17H15BrN2S

Molecular Weight

359.28

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Kovács T, et al. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci Rep. 2017 Feb 16;7:42014.