Deoxycytidine triphosphate-13C9,15N3 (dilithium)

Deoxycytidine triphosphate-13C9,15N3 (dCTP-13C9,15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate-13C9,15N3) dilithium is 13C and 15N-labeled Deoxycytidine triphosphate (HY-101400) . Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

Product Specifications

Product Name Alternative

DCTP-13C9,15N3 (dilithium) ; 2′-Deoxycytidine-5′-triphosphate-13C9,15N3 (dilithium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/deoxycytidine-triphosphate-13c9-15n3-dilithium.html

Solubility

10 mM in DMSO

Smiles

O[13C@H]1[13CH2][13C@H]([15N]2[13C]([15N]=[13C]([15NH2])[13CH]=[13CH]2)=O)O[13C@@H]1[13CH2]OP(OP(OP(O)(O[Li])=O)(O[Li])=O)(O)=O

Molecular Formula

13C9H14Li2 15N3O13P3

Molecular Weight

490.94

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]M H Tattersall, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975 Apr;5 (2) :191-202.|[3]A W Harris, et al. Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1979 Feb;39 (2 Pt 1) :538-41.|[4]B A Bladergroen, et al. CTP:phosphoethanolamine cytidylyltransferase. Biochim Biophys Acta. 1997 Sep 4;1348 (1-2) :91-9.