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CGP 54626 (hydrochloride)

CGP 54626 (hydrochloride) is a selective antagonist of GABAB receptor with an IC50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABAB receptors in neurological signaling[1].

Product Specifications

CAS Number

[149184-21-4]

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cgp-54626-hydrochloride.html

Purity

99.76

Solubility

10 mM in DMSO

Smiles

O=P(C[C@@H](O)CN[C@H](C1=CC=C(Cl)C(Cl)=C1)C)(CC2CCCCC2)O.Cl

Molecular Formula

C18H29Cl3NO3P

Molecular Weight

444.76

References & Citations

[1]Kaupmann K, et al. GABA (B) -receptor subtypes assemble into functional heteromeric complexes. Nature. 1998 Dec 17;396 (6712) :683-7.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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