LY 235959
LY 235959 is a competitive N-methyl-D-aspartate (NMDA) -receptor antagonist. LY 235959 potentiates the anticonvulsant action of antiepileptics[1].
Product Specifications
CAS Number
[137433-06-8]
Product Name Alternative
(-) -LY 235959
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-235959.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H]1C[C@]2([H])[C@@](CN1)([H])CC[C@@H](C2)CP(O)(O)=O)=O
Molecular Formula
C11H20NO5P
Molecular Weight
277.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]K K Borowicz, et al. Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice. Epilepsia. 1996 Jul;37 (7) :618-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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