Xamoterol

Xamoterol is a selective and potent agonist of beta1-adrenergic receptor. Xamoterol has the potential for the research of arrhythmogenesis. Xamoterol has the potential for the investigating the relationship between β1-adrenergic stimulation and IKr[1].

Product Specifications

CAS Number

81801-12-9

Product Name Alternative

Corwin; ICI 118587

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/xamoterol.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCOCC1)NCCNCC(O)COC2=CC=C(O)C=C2

Molecular Formula

C16H25N3O5

Molecular Weight

339.39

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Wang S, et al. β1-adrenergic regulation of rapid component of delayed rectifier K+ currents in guinea-pig cardiac myocytes. Mol Med Rep. 2014;9 (5) :1923-1928.