MK-212

MK-212 (CPP) is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 can stimulate phosphoinositide hydrolysis in cerebral cortex[1].

Product Specifications

CAS Number

[64022-27-1]

Product Name Alternative

CPP

UNSPSC

12352005

Hazard Statement

H317-H319

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mk-212.html

Solubility

10 mM in DMSO

Smiles

ClC1=NC(N2CCNCC2)=CN=C1

Molecular Formula

C8H11ClN4

Molecular Weight

198.65

Precautions

P261-P264-P272-P280-P302+P352-P362+P364-P501

References & Citations

[1]Lee HS, et, al. Effect of the serotonin agonist, MK-212, on body temperature in schizophrenia. Biol Psychiatry. 1992 Mar 1;31 (5) :460-70.|[2]Conn PJ, et, al. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther. 1987 Aug;242 (2) :552-7.