ZD-7114 (hydrochloride)
ZD-7114 hydrochloride is a potent and selective agonist of β3-adrenergic. ZD-7114 hydrochloride is a selective thermogenic agent in vivo. ZD-7114 hydrochloride can be used in study obesity and diabetes[1].
Product Specifications
CAS Number
129689-28-7
Product Name Alternative
ICI-D 7114 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H400
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/zd-7114-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOC)COC1=CC=C(OCCNC[C@H](O)COC2=CC=CC=C2)C=C1.Cl
Molecular Formula
C22H31ClN2O6
Molecular Weight
454.94
Precautions
P273-P391-P501
References & Citations
[1]Howe, Ralph, et al. Selective .beta.3-adrenergic agonists of brown adipose tissue and thermogenesis. 2. [4-[2-[ (2-Hydroxy-3-phenoxypropyl) amino]ethoxy]phenoxy]acetamides. Journal of Medicinal Chemistry, 35 (10), 1759–1764.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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