ZD-7114 (hydrochloride)

ZD-7114 hydrochloride is a potent and selective agonist of β3-adrenergic. ZD-7114 hydrochloride is a selective thermogenic agent in vivo. ZD-7114 hydrochloride can be used in study obesity and diabetes[1].

Product Specifications

CAS Number

[129689-28-7]

Product Name Alternative

ICI-D 7114 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H400

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/zd-7114-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCOC)COC1=CC=C(OCCNC[C@H](O)COC2=CC=CC=C2)C=C1.Cl

Molecular Formula

C22H31ClN2O6

Molecular Weight

454.94

Precautions

P273-P391-P501

References & Citations

[1]Howe, Ralph, et al. Selective .beta.3-adrenergic agonists of brown adipose tissue and thermogenesis. 2. [4-[2-[ (2-Hydroxy-3-phenoxypropyl) amino]ethoxy]phenoxy]acetamides. Journal of Medicinal Chemistry, 35 (10), 1759–1764.