TRIM
TRIM is a potent nitric oxide synthase inhibitor. TRIM inhibits mouse cerebellar nNOS and rat lung iNOS in vitro with IC50 values of 28.2 and 27.0 μM, respectively. Antidepressant- and anxiolytic-like effects[1][2].
Product Specifications
CAS Number
[25371-96-4]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trim.html
Purity
99.90
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
FC(C1=CC=CC=C1N2C=CN=C2)(F)F
Molecular Formula
C10H7F3N2
Molecular Weight
212.17
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101316/TRIM-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101316/TRIM-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
INOS; nNOS
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