ICI 192605
ICI 192605 is a potent TXA2R (thromboxane A2 receptor) antagonist as cell signaling prostaglandin. ICI 192605 blocks contraction of isolated guinea pig trachea induced by U-46619[1].
Product Specifications
CAS Number
[117621-64-4]
UNSPSC
12352005
Hazard Statement
H302-H410
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ici-192605.html
Solubility
10 mM in DMSO
Smiles
OC(CC/C=C\C[C@@H]1[C@H](C(C=CC=C2)=C2O)O[C@H](C(C=CC=C3)=C3Cl)OC1)=O
Molecular Formula
C22H23ClO5
Molecular Weight
402.87
Precautions
P264-P270-P273-P330-P391-P501
References & Citations
[1]Brewster AG, et al. The synthesis of a novel thromboxane receptor antagonist 4 (Z) -6- (2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid ICI 192605. Prostaglandins. 1988 Aug;36 (2) :173-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
TXA2/TP
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1123308-01 0.02 mg (E-Coli)
Recombinant Bacillus subtilis Uncharacterized protein ywmB (ywmB)
Ask
View Details MBS1123308-02 0.1 mg (E-Coli)
Recombinant Bacillus subtilis Uncharacterized protein ywmB (ywmB)
Ask
View Details 
MBS1123308-03 0.02 mg (Yeast)
Recombinant Bacillus subtilis Uncharacterized protein ywmB (ywmB)
Ask
View Details MBS1123308-04 0.1 mg (Yeast)
Recombinant Bacillus subtilis Uncharacterized protein ywmB (ywmB)
Ask
View Details MBS1123308-05 0.02 mg (Baculovirus)
Recombinant Bacillus subtilis Uncharacterized protein ywmB (ywmB)
Ask
View Details