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ICI 174864

Product Specifications

UNSPSC Description

ICI 174864 is a highly selective, potent δ-receptor antagonist. ICI 174864 is equipotent with naloxone and can not reverse the effect of the μ-agonist [D-Ala2, MePhe4, Gly-Ol5]enkephalin or the κ-agonist-tifluadom[1].

Target Antigen

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ici-174864.html

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=CCN(CC=C)[C@H](C(NC(C)(C)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC1=CC=CC=C1)=O)=O)CC2=CC=C(C=C2)O

Molecular Weight

606.75

References & Citations

[1]R Cotton, et, al. ICI 174864: a highly selective antagonist for the opioid delta-receptor. Eur J Pharmacol. 1984, 97,3.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-101230/ICI-174864-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-101230/ICI-174864-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

89352-67-0

Curated Selection

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