(2R,3S) -Chlorpheg

(2R,3R) -Chlorpheg is a week antagonist of L-homocysteic acid (L-HCA) induced depolarization. (2R,3R) -Chlorpheg also is a weak N-methyl-D-aspartate (NMDA) antagonist[1].

Product Specifications

CAS Number

[140924-23-8]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2r-3r-chlorpheg.html

Solubility

10 mM in DMSO

Smiles

N[C@H]([C@@H](C1=CC=C(Cl)C=C1)CC(O)=O)C(O)=O

Molecular Formula

C11H12ClNO4

Molecular Weight

257.67

References & Citations

[1]D J Chalmers, et, al. Differential actions of 3- (4-chlorophenyl) glutamic acid stereoisomers and L-trans-pyrrolidine-2,4-dicarboxylic acid upon L-homocysteic acid- and L-glutamic acid-induced responses from rat spinal motoneurones. Neuropharmacology. 1995, 34, 12.