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UK-371804 (hydrochloride)

UK-371804 hydrochloride (compound 24) is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM[1].

Product Specifications

CAS Number

256476-36-5

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PAI-1

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/uk-371804-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CC(C(O)=O)(C)NS(=O)(C1=CC2=C(C=C1)C(Cl)=CN=C2NC(N)=N)=O.Cl

Molecular Formula

C14H17Cl2N5O4S

Molecular Weight

422.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Paul V Fish, et al. Selective urokinase-type plasminogen activator inhibitors. 4. 1- (7-sulfonamidoisoquinolinyl) guanidines. J Med Chem. 2007, 50, 10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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