UK-371804 (hydrochloride)
UK-371804 hydrochloride (compound 24) is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM[1].
Product Specifications
CAS Number
256476-36-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PAI-1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/uk-371804-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CC(C(O)=O)(C)NS(=O)(C1=CC2=C(C=C1)C(Cl)=CN=C2NC(N)=N)=O.Cl
Molecular Formula
C14H17Cl2N5O4S
Molecular Weight
422.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Paul V Fish, et al. Selective urokinase-type plasminogen activator inhibitors. 4. 1- (7-sulfonamidoisoquinolinyl) guanidines. J Med Chem. 2007, 50, 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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