GJ103

GJ103 is a read-through compound that can induce read through of premature stop codons. GJ103 has potential for the research of genetic disorders caused by nonsense mutations[1].

Product Specifications

CAS Number

[1459687-89-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gj103.html

Solubility

10 mM in DMSO

Smiles

OC(CSC1=NN=C(N1C2=CC=CC(OC)=C2)C3=NC=CC=C3)=O

Molecular Formula

C16H14N4O3S

Molecular Weight

342.37

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Du L, et, al. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Mol Ther. 2013 Sep;21 (9) :1653-60.