DL-erythro-Dihydrosphingosine
DL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2) [1][2].
Product Specifications
CAS Number
3102-56-5
UNSPSC
12352211
Target
Phospholipase; PKC
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dl-erythro-dihydrosphingosine.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCC[C@H](O)[C@H](N)CO
Molecular Formula
C18H39NO2
Molecular Weight
301.52
References & Citations
[1]R Chao, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25;267 (33) :23459-62.|[2]Hiroyuki Nakamura, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004 Jan 19;484 (1) :9-17.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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