DL-erythro-Dihydrosphingosine
Product Specifications
UNSPSC Description
DL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2)[1][2].
Target Antigen
Phospholipase; PKC
Type
Reference compound
Related Pathways
Epigenetics;Metabolic Enzyme/Protease;TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dl-erythro-dihydrosphingosine.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCC[C@H](O)[C@H](N)CO
Molecular Weight
301.52
References & Citations
[1]R Chao, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25;267(33):23459-62.|[2]Hiroyuki Nakamura, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004 Jan 19;484(1):9-17.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101195/DL-erythro-Dihydrosphingosine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101195/DL-erythro-Dihydrosphingosine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3102-56-5
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